The drug is contraindicated in patients with hypersensitivity to active substances or to any other component of the drug, other aminoglycoside antibiotics (cross-allergic reactions to gentamicin) or imidazole derivatives (cross-allergic reactions to clotrimazole). And also with tuberculosis of the skin, skin manifestations of syphilis, skin reactions after vaccination, skin ulcers, acne, common plaque psoriasis, viral skin infections (for example, herpes simplex, shingles), varicose veins, perioral dermatitis, rosacea, chickenpox other bacterial and fungal infections of the skin without proper antibacterial and antifungal therapy. Triderm is not indicated for use with occlusive dressings. Triderm should not be applied to mucous membranes, eyes or the area around the eyes. Do not use the cream to treat nails or scalp infections.