This response is mediated by the discharge of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in clean muscle cells. Cyclic GMP causes easy muscle rest and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase kind five (PDE5) by means of tadalafil complements erectile function with the aid of increasing the amount of cGMP.
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This response is mediated by the discharge of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in clean muscle cells. Cyclic GMP causes easy muscle rest and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase kind five (PDE5) by means of tadalafil complements erectile function with the aid of increasing the amount of cGMP.
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