Progestins are a class of hormones that are often used in transgender hormone therapy. They can help to suppress testosterone production, and they also have feminizing effects on the body. There are many different types of progestins, and each one has its own unique set of benefits and drawbacks. Some common progestins used in transgender #hormone #therapy include medroxyprogesterone acetate (MPA), norethindrone acetate (NETA), and dienogestrel (DNG). MPA is a very popular progestin for transgender #hormone therapy because it has strong anti-androgenic effects. It can help to reduce testosterone levels significantly, which can lead to breast growth, decreased facial hair growth, and other feminizing effects. However, MPA can also cause some side effects such as weight gain, mood swings, and headaches. NETA is another common #progestin that is often used in transgender hormone therapy. It has similar anti-androgenic effects as MPA but tends to cause less weight gain and mood swings. However, NETA may not be as effective at suppressing #testosterone levels as MPA is. DNG is another popular progestin that is sometimes used in transgender hormone therapy . Like NETA , DNG has anti -androgenic properties , but it also seems to have estrogenic properties . This means that it can help with things like breast growth , bone mineral density improvement , fat redistribution , etc . DNG does not seem to cause the same level of side -effects as MPA or NETA do; however, more research needs to be done on this particular #drug #health