What to know about tadalafil Tadalafil is a medication prescribed to treat erectile dysfunction (ED). The drug increases blood flow to the penis during sexual stimulation.To get more news about http://www.vigrxplus-original.com/VigRX-Plus.html vigrx plus price, you can visit vigrxplus-original.com official website. ED relates to the difficulty a person may have achieving or maintaining an erection. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) states that approximately 30 million menTrusted Source in the United States may have this health condition. Additionally, a recent study found that ED was common in a cohort of sexually active men aged between 18–31 years in the US. The study found that relationship status and mental health were the most significant contributing factors. Brand-name vs. generic drugs When a pharmaceutical company develops a new drug, it must obtain a New Drug Approval (NDA)Trusted Source from the Food and Drug Administration (FDA). Once granted, there is an exclusivity period in which no other company may produce the same drug using the same active ingredients. Periods of exclusivity can last from 180 days to 7 yearsTrusted Source. After this time, other manufacturers are free to make generic versions of a drug under an Abbreviated New Drug Application (ANDA)Trusted Source. It is “abbreviated” because generic drug developers do not have to submit the preclinical and clinical testing data supplied by the original pharmaceutical company. This also accounts for the difference in brand-name and generic drug costs. Tadalafil is the generic name for the brand-name drug Cialis. At the time of publishing, the average cash price of 30, 10-milligram (mg) Cialis tablets is approximately $2,524.92, whereas tadalafil is around $1,603.20, making it far more cost effective. Some online companies, such as GoodRx, also offer discount coupons that dramatically lower prices. For example, the same dose and quantity of tadalafil tablets using a GoodRx coupon at Food Lion Pharmacy costs $17.00. How tadalafil works Tadalafil is part of the class of phosphodiesterase (PDE5) inhibitors that treat people with high blood pressure in the lungs’ arteries, also known as pulmonary hypertension, ED, and an enlarged prostate known as benign prostatic hyperplasia. PDE5 inhibitors work by increasing blood flow to the penis. They block a specific enzyme in the blood vessels. This means these blood vessels can relax, resulting in an increased blood flow to a specific area. The effects of tadalafil can last for 36 hours. This is significantly longer than the similar drug, sildenafil (brand name Viagra), which lasts approximately 4 hours. A person may consider this an advantage or a disadvantage.