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- EASY WAYS TO IMPROVE SCIATICA PAINSciatica, or inflammation of the sciatic nerve, affects up to four out of every ten people at some point in their lives. This nerve goes through the pelvis and buttocks and originates on each side of the lower spine. The nerve then travels down the back of each upper leg before splitting into branches that lead to the foot at the knee. Anything that irritates or presses on this nerve might...