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- Composed Of Psychedelic Magic Mushrooms, Psilocybin Behaves At Least As Well As The Main AntidepressantIn a therapeutic environment, psilocybin, the main component in magic mushrooms, may be at least as effective as a leading antidepressant medicine. This is the conclusion of a study conducted by experts at Imperial College London's Centre for Psychedelic Research. Researchers compared two sessions of psilocybin therapy with a six-week course of a leading antidepressant (a selective serotonin...