The Giants (2-3) travel to take on the Patriots (5-0) as 17-point road underdogs on Thursday Night Football in Week 6. In a rematch of Super Bowls XLII and XLVI, rookie Daniel Jones will make the fourth start of his career after replacing the two-time Super Bowl MVP Eli Manning in Week 3. While this game sounds like a mismatch to most, there are some interesting betting opportunities, especially against the spread.

The Giants won back-to-back games against the Tampa Bay and Washington before losing 28-10 to Minnesota last Sunday. Unfortunately, they will now have to face the NFLs top defense in Foxboro, where New England has not lost since 2017. The undefeated Patriots have outscored opponents by 121 points (155-34) through five Chris Long Men Jersey games. For reference, thats the second-best scoring margin since the AFL-NFL merger in 1970 behind only the 1999 "Greatest Show on Turf" Rams.

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Giants Outlook

If the Giants hope to win or even just cover against New England, they will need new playmakers Malik Jackson Men Jersey to step up. They will be without their top two rushers this season -- running backs Saquon Barkley (ankle) and Wayne Gallman (concu sion) -- along with their top two pa s-catchers -- tight end Evan Engram (knee) and wide receiver Sterling Shepard (concu sion).

Despite the lo ses at running back, it is imperative that the Giants stick with the run to keep this New England defense honest. If the Giants become one dimensional -- as they did last Sunday by throwing the ball two thirds of the time -- then things could get ugly quickly for Daniel Jones against a Van Jefferson Women Jersey defense that has given up just two touchdowns all season. The Patriots pa s rush is especially dangerous,as it leads the NFL with 24 sacks (four more than Panthers). The defense also has four more interceptions than any other team (11). The Giants will use the tandem of undrafted rookie running back Jonathan Hilliman and third-year fullback Elijhaa Penny on the ground this week. They combined for 12 rushes for 35 yards against Minnesota on Sunday. New York will also need receivers to step up. Rookie receiver Darius Slayton out of Auburn led all New York receivers with 62 yards and a touchdown against Minnesota. New acquisition Golden Tate will also need to improve on his first outing as a Giant where he caught just three of six targets for 13 yards. He could easily see double-digit targets in this one.

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Despite only scoring 10 points against Minnesota, Jones was 8-for-16 on third-down attempts. He led the Giants up and down the field but could not capitalize in the red zone, especially after Gallman went down with an injury. Jones and the Giants offense will need to continue their third-down succe s against a Patriots defense that has allowed offenses to convert just 12.7 percent of their third-down opportunities. Therefore, it will certainly be a Aqib Talib Women Jersey tall task.

Last week, the Giants defense recorded three sacks in its fourth consecutive game, but it only collected four total hits on Kirk Cousins. The Vikings ran all over the Giants for 211 yards on 6.2 yards Maurkice Pouncey Women Jersey per carry and kept New Yorks defense on its heels all day. The Giants will not face the same caliber of rushing attach this week, as the Patriots average just 3.5 yards per carry (27th in the NFL) while the Vikings have averaged 5.4 yards per carry (T-3rd) through five weeks. The Giants defense ranks tied for 14th with 4.4 yards per carry allowed. It will welcome back inside linebacker Alec Ogletree from injury to help against the run, but his contributions to the pa s rush will also be noted, as he leads New Yorks linebackers with five pre sures this season.

New York could benefit from the Patriots willingne s to run the football and milk the clock if they get out to an early lead. With such a large spread, they could lose by two touchdowns and still cover.

So far, just 37 percent of public bets and 21 percent of the money has been wagered Josh Hill Men Jersey on the Giants (per dashboard). So, this is a sneaky spot.

Patriots outlook

The Patriots are undefeated this season, and thus far -- just like in the Super Bowl in February -- the defense has led the way. The Patriots have the best scoring defense (6.8 points per game allowed) while recording the most interceptions, sacks, and pa ses defended through five games. They also have allowed the fewest pa sing yards per game (160.4) and total yards per game (238.4) while recording the most sacks per pa s attempt (13.4percent). Devin McCourty (four) and Jamie Collins (three) lead the league in interceptions and have combined for as many picks as any other team. This has helped the Patriots maintain the best turnover margin (plus-seven) in the NFL.

While the defense has dominated through five weeks, the offense has some question marks going into this weeks Thursday night matchup. The Patriots offensive line allowed a season-high 11 disruptions of Tom Brady against lowly Washington this week (four sacks, two QB hits, five pre sures). They matched their prior season high by allowing nine disruptions in the first half alone. It didnt help LeSean McCoy Men Jersey that the Patriots were one dimensional in the first half, as they ran the ball just seven times while pa sing 34 times. The Patriots have already lost their starting left tackle Isaiah Wynn to IR and center David Andrews for the season.

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Just like the Giants, the Patriots also have a long list on the injury report this week. Receiver Phillip Dorsett has been ruled out. Six more Patriots are questionable: RB Rex Burkhead, LBShilique Calhoun, S Patrick Chung, S Nate Ebner, WR Julian Edelman, and WR Josh Gordon. Burkhead, Chung, and Ebner all sat out last week against Washington. Thus New Englands top two receivers are both questionable, and their third is out against the Giants.

The Patriots have also failed to find consistent TE play in Tracy Walker Men Jersey the receiving game in life after Rob Gronkowski. Ryan Izzo leads all tight ends with just 83 yards receiving this season. Like the Giants, the Patriots will need to stick with the run, especially if Edelman and/or Gordon are out as receivers may struggle to get separation down the field.

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Prediction

Although the Patriots and their defense are on a historic pace, they have done so largely against some of the NFLs worst teams. Aside from the Bills, the rest of New Englands opponents have a combined record of 1-17. The only legitimate defense that Brady and company faced (Buffalo) gave them fits, as the Patriots won 16-10 Ronnie Stanley Men Jersey and Tom Brady recorded his lowest pa ser rating in a win in 13 seasons. Bradys 31.9-percentcompletion rate when pre sured ranks last among 13 quarterbacks with a minimum of 190 drop-backs.

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Without the same presence on the offensive line and at the tight end position that people have grown accustomed to Jim McMahon Men Jersey seeing in New England, the Patriots offense could continue to struggle against competitive defenses. The receiver position was already a question mark for New England coming into the season, but adding injuries into the mix severely limits the big-play potential in Thursdays matchup against the Giants with Edelman and Gordon banged up.

The Patriots should win this game outright, but dont be surprised if the Giants cover and keep this game somewhat competitive. Or, if the game gets out of hand, expect Bill Belichick and company to run the football and potentially even pull their starters, thus diminishing their overall scoring potential.

Check out BetQL to see what teams our models are on in Week 6!